Clinical Management of Multidrug-Resistant Pulmonary Tuberculosis in Geriatric: A Case Study at RSUD Prof. Dr. Aloei Saboe

Authors

  • Dizky R. Papeo Universitas Negeri Gorontalo
  • Tita Arikah Aulia Universitas Negeri Gorontalo
  • Siti Dinarti Husain Universitas Negeri Gorontalo
  • Selviana Selviana Universitas Negeri Gorontalo
  • Jhuandaniel Piator Pangaribuan Universitas Negeri Gorontalo
  • Alvionita B. Anwar Universitas Negeri Gorontalo

DOI:

https://doi.org/10.53861/lontarariset.v7i1.644

Keywords:

Clinical Management, Drug Related Problem, Geriatric, Multidrug-resistant tuberculosis

Abstract

Drug-resistant pulmonary tuberculosis (DR-TB) is a challenging form of TB characterized by resistance to at least rifampicin and isoniazid, requiring the use of complex second-line therapies. This condition is often accompanied by complications that further aggravate the clinical course. The aim of this study was to evaluate the management of DR-TB with complications. This retrospective case study was based on the medical record of a 63-year-old female patient with a history of TB in 2020 who was diagnosed with relapsed DR-TB complicated by hypertension, anemia, and insomnia. The diagnosis was confirmed through a rapid molecular test showing a positive result for Mycobacterium tuberculosis with rifampicin resistance. Initial management included the administration of second-line antibiotics, blood transfusion to address anemia, and supportive care for accompanying symptoms. Following two consecutive positive results, the patient commenced second-line anti-tuberculosis (ATT) therapy according to MDR-TB treatment standards. Evaluation revealed improvement in hemoglobin levels after transfusion, although shortness of breath persisted and required further monitoring. In conclusion, the management of DR-TB with complications requires a multidisciplinary approach tailored to the patient’s clinical condition

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Published

2026-01-15

How to Cite

Papeo, D. R., Aulia, T. A., Husain, S. D., Selviana, S., Pangaribuan, J. P., & Anwar, A. B. (2026). Clinical Management of Multidrug-Resistant Pulmonary Tuberculosis in Geriatric: A Case Study at RSUD Prof. Dr. Aloei Saboe . Lontara Journal of Health Science and Technology, 7(1), 145–155. https://doi.org/10.53861/lontarariset.v7i1.644

Issue

Vol. 7 No. 1 (2026): Januari-Juni 2026

Section

Review Article

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Copyright (c) 2026 Dizky R. Papeo, Tita Arikah Aulia, Siti Dinarti Husain, Selviana Selviana, Jhuandaniel Piator Pangaribuan, Alvionita B. Anwar

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